'How to create context-sensitive hotkeys when no window is active?

I want to create some hotkeys when no window is active:

But there's no statement like #IfNoWinActive, how to achieve this?

Solution 1:^[1]

~Esc::
  WinGet A, PID, A

  if !A {
    MsgBox ; ? put logic here
  }
  return

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Solution	Source
Solution 1	Wenfang Du