How to perform deletion, addition or merging operations on Miasm AsmBlocks?

Question

Using Python 3 and the framework Miasm, I am trying to parse a binary and simplify its code. After parsing it, I have a list of AsmBlock objects that prints like this:

loc_401c05
MOV        BYTE PTR [RBP + 0xFFFFFFFFFFFFFFC0], 0x0
XOR        DWORD PTR [RBP + 0xFFFFFFFFFFFFFFCC], 0xF
MOV        DWORD PTR [RBP + 0xFFFFFFFFFFFFFFC8], 0x12345678
JMP        loc_402f0c
->  c_to:loc_402f0c 

loc_401c19
MOV        DWORD PTR [RBP + 0xFFFFFFFFFFFFFFF8], 0x1
XOR        DWORD PTR [RBP + 0xFFFFFFFFFFFFFFCC], 0x18
MOV        DWORD PTR [RBP + 0xFFFFFFFFFFFFFFC8], 0x12345678
JMP        loc_402f0c
->  c_to:loc_402f0c

and I would like to do things like deleting some instructions, adding some custom jumps and merging blocks to patch later the binary with the resulting blocks (it indeed sounds a hassle, but the goal is to remove obfuscation, so I have no other choice). However, I fail at finding how to do so, and Miasm documentation is quite bad. I am not even sure that I am manipulating the correct object, as calling dir on one of them does not show a lot of functions appropriate for such modifications:

[(...), '_filter_constraint', '_loc_key', 'add_cst', 'addline', 'addto', 'alignment', 'bto', 'fix_constraints', 'get_flow_instr', 'get_next', 'get_offsets', 'get_range', 'get_subcall_instr', 'lines', 'loc_db', 'loc_key', 'split', 'to_string']

How should I proceed?