graphs for evolution with Seaborn or Matplotlib ( many columns as X axis , very column holds a number )

Question

I want to produce a graph with Seaborn or Matplotlib of the evolution of population for different regions , during different years.

I want all the columns to be in X axis, and the population count in Y axis, and every line will be representative to a specific region, so different colours.

Does anyone know how to display this ?

Here is my data frame in the image below.

Thanks in advance.