'Only allowed certain string in a column to be send to MySQL

I have a question. Am I able to allow only certain strings to be place into a DataFrame and then uploaded to MySQL?

For example, I want to only allow 'A' and 'B' onto MySQL with the column name of 'Channel'. I have an idea of doing it as followed:

if 'A' and 'B' not in df['Channel']:
    pass

But it seems that there is still some strings which are not related would be send onto it. So is there any way to do this?

python pandas

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