Keep SQLite table synced using data taken from Excel sheet (without passing through CSV conversion)

Question

I am looking for a way to use one excel sheet as data source for a SQLite DB. My goal is to have the database table updated when I change something in excel, automatically would be the best of course, or manually by any simple mean: one macro, one prompt command, batch script whatever, as long it doesn't require more than a couple of mouse clicks.

I have explored other solutions like passing through CSV files and it is not viable, it takes less time to manually update the data directly into SQLite...

Thanks in advance.