Reload user control after download file

Question

In one of forms in my webform project, there is a user control. this is what I want to do When user click on "download" button in this user control:

1. download file
2. change a related record in db (for change user status)
3. reload that user control (or whole form) to show information based on new status.

I try this solution but the user control doesn't reload.This is body of onclick event :

  Response.Redirect("~/Handlers/DownloadFile.ashx?FilePath=CourseFiles/" + _secondFilePath, false);
                _secondFilePath = string.Empty;
                CourseDB.ChangeCourseStep(DB.CurrentUser.ID, _lastUnpassedCourseInfo.CourseID, (int)Data.Enums.CourseStep.SecondPartFilesDownloaded);
                Response.AddHeader("Refresh", "3; url=~/Profile/SalesEngineeringCourse.aspx");
                Response.End();

and this is body of HttpHandler :

 public void ProcessRequest(HttpContext context)
    {
        string filePath = HttpContext.Current.Request.QueryString["FilePath"];
        string fileName = filePath.Split('\\').Last();
        string fileType = filePath.Split('.').Last();
        System.Web.HttpResponse response = System.Web.HttpContext.Current.Response;
        response.ClearContent();
        response.Clear();
        response.ContentType = fileType;
        response.AddHeader("Content-Disposition",
                           "attachment; filename = " + fileName);
        response.TransmitFile(System.Web.HttpContext.Current.Server.MapPath("~") + filePath);
        response.Flush();
    }

    public bool IsReusable
    {
        get
        {
            return false;
        }
    }

is there any solution for this?