'Is there a way to exploit BitBoard advantages on a 4x16 gameboard?

So basically the title. The gameboard looks like this:

0000 0000 0000 0000

I cant wrap my head around, if it is possible to use the BitBoard logic on this kind of board?

If it is possible is there an advantage doing it?

Or can BitBoard logic only be used for square boards ?

bitboard

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