How to append client-side scripts to page in Node

Question

I'm starting project ts, node, express. Is there a way to add typescript files to html/ejs that run on client side (so i have access to document e.t.c., just like in regular js script)?

So it would be something like:

• Node server with express that returns html pages and handles users sign in/up requests.
• Adding, deleting, changing elements in html on user's activity handles in scripts on client side.

I would appreciate pointing on what I misunderstood in whole node, express conception if I did.